Towards bacterial chemical glycobiology
發布時間 🥕:2018-03-26  閱讀次數 ♐️:4684

報告題目🫶🏼:Towards bacterial chemical glycobiology

報  告 人🚏:李學臣  教授  香港大學

報告時間: 3月30日,10:00-11:30

報告地點🐖:閔行校區生物藥學樓3-105會議室

聯  系 人👩🏻‍🎓:林雙君 linsj@sjtu.edu.cn

 

報告摘要:

To study proteins carrying post-translational modifications, chemical biology approach provides new tools to gain new insights to their biological significance. Over the year, we have developed novel methods to generate homogeneous proteins with site-specific modification structures and modify proteins. In particular, bacterial protein glycosylation has emerged as a new entry to study bacterial pathogenesis and develop novel therapeutic intervention. For instance, P. aeruginosa 1244 pilin is glycosylated with a trisaccharide and the exact biological function of Pse-containing glycans in bacterial glycoproteins remains elusive. In this presentation, we will report our efforts in developing chemical biology tools to study bacterial glycobiology.

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